Nucleophile In Sentences - Examples Of Nucleophile In Sentences

Search your words in sentences https://englishteststore.net/index.php?option=com_content&view=article&id=20211&Itemid=1131 - Metal ions are particularly effective and can reduce the pKa of water enough to make it an effective nucleophile. - A Glu residue has been proposed as a catalytic residue, but it is not known if it is the nucleophile or the proton donor. - how would a nucleophile distort that orbital? - Depending on the nature of the Lewis acid used, coordination of the nucleophile to the Lewis acid may be significant. - Triggering can also occur via attack by an external nucleophile. - The nucleophile forms a bond with its lone pair as the electron source. - Additionally, organoboranes can serve the role of the nucleophile and often provide higher yields with fewer complications than analogous carbanions. - The process is highly dependent on the solvent, nature of the nucleophile, and moieties in the compound. - But to address the first problem, we could choose a mixture of methylene chloride and ether to try to solvate the acid, and choose a strong acid whose conjugate base makes a poor nucleophile... - A nucleophile will attack the double bond in the variable region, causing a chain reaction of electron pushing. - The electrostatically held nucleophile can exchange positions with a ligand in the first coordination sphere, resulting in net substitution. - However, upon activation by a nucleophile, the resulting aluminates are highly nucleophilic and add to electrophiles with retention of configuration at the migration carbon. - Find the places of high electron density and find the places of low electron density, thats your nucleophile and electrophile respectively. - Is hypochlorite that good of a nucleophile? - The chlorine is likely just a good enough nucleophile to substitute here. - It is unstable at room temperature, owing to the incompatibility of the amine nucleophile and the nitrile electrophile. - When the nucleophile is an organometallic reagent, the mechanisms of the first step can vary. - I was thinking decarboxylation effectively creates a carbanion nucleophile, which would go on to attack an alkyl halide ... - The chiral ketene enolate nucleophile attacks electrophilic carbon of the imine group. - Like organoboranes, organoalanes possess an empty p orbital on the aluminium center that can receive electron density from an added nucleophile. - This strong nucleophile can then be used as such with other electrophiles. - The rate of reaction of nucleophile and electrophile depends on the identity of both. - Solvolysis in the presence of a nucleophile such as acetic acid reverses the cyclopropylcarbinyl transformation to afford homoallylic acetate. - Unlike many other bases, the steric bulk prevents this base from acting as a nucleophile. - The first residue of the second portion of the extein must be a serine, threonine or cysteine as well, and this second nucleophile forms a branched intermediary. - The thiourea hydrogen bonds to the nitro group and stabilizes the incoming negative charge, while the amine acts a specific base to activate the nucleophile. - These residues act as a nucleophile, with the glutamic acid serving as a general acid in the first phase of the reaction, donating a proton to the carbonyl oxygen in the peptide bond of the substrate. - It is believed that the pH of the reaction will affect the existing form of the amine nucleophile, which will determine whether the nitrogen coordinates with palladium center or not during the aminopalladation step. - The iminium ion is then quenched by reaction with a nucleophile. - The nucleophile then attacks the carbocation, forming the product. - It is a nucleophile and a strong base. - Successive reactions with suitable nucleophile are able to proceed on the electrophilic phosphorus atom. - During the attack of the nucleophile, negative charge builds on the oxygen until the tetrahedral intermediate is reached. - Therefore, to terminate the polymerization, a quenching agent must be added, such as a strong acid to protonate the polymer, or a nucleophile to add an end cap the polymer. - In the second step, the chloride nucleophile attacks the carbocation to form the product. - First it acts as a general base to activate water as a nucleophile. - While a carbon nucleophile will react with the acid halide first to produce a ketone, the ketone is also susceptible to nucleophilic attack, and can be converted to a tertiary alcohol. - Isotope exchange studies indicate that for aryl fluorides and, sometimes, aryl chlorides, the elimination event proceeds in two steps, deprotonation, followed by expulsion of the nucleophile.